Diagnosis

Diagnosing pancreatic cancer

Any symptoms people do have can be quite vague and may also be a sign of other more common illnesses which affect the gastro-intestinal system (GUT) such as hepatitis, pancreatitis, gallstones, irritable bowel syndrome or even stress. So it can be particularly difficult for GPs to detect and diagnose pancreatic cancer, especially in its early stages. As there is currently no easy way of detecting pancreatic cancer, diagnosis may sometimes be delayed while GPs or specialists spend time ruling out all the different possible causes for people's symptoms. You can read more here about signs and symptoms of pancreatic cancer. 

Routes to diagnosing pancreatic cancer

The difficulty doctors have in detecting and diagnosing pancreatic cancer means that people may arrive at a firm diagnosis by different routes.

GP visit

Most people start by seeing their GP. Sometimes people may see their GP several times because of vague symptoms that don't get better over time. As with any illness, if your symptoms persist it's important to go back to your GP until you get a firm diagnosis or a referral for further investigations.

Your GP will begin by asking you about your symptoms, which may or may not be obvious.

  • They will usually look at your eyes and the colour of your skin for signs of jaundice.
  • They may also examine your abdomen (tummy) for any swelling and to check if it is tender or painful.
  • They will probably test your urine for bile.
  • They may also take a blood sample.
  • They may ask you whether you have had any problems with eating, or digesting your food, and whether your bowel habit has altered
  • They may ask you whether you have been losing weight

Your GP may decide to refer you to your local hospital for tests and to see a specialist.

Some symptoms indicate that your GP should refer you to a team specialising in pancreatic disease (an upper gastrointestinal or hepatobiliary team) straight away. These symptoms include jaundice, persistent unexplained abdominal pain and unexplained weight loss. This is known as an urgent referral for suspected cancer and means you should be seen by a specialist within two weeks. Being referred urgently does not necessarily mean that you do have cancer.

The National Institute for Health and Clinical Excellence (NICE) has produced guidelines to help GPs with their decision-making and you can read more about them here.

If you are very unwell when you see your GP they may decide to send you straight to hospital for assessment and further investigations as an outpatient, or they may feel it is more appropriate to arrange your admission as an emergency.

Referral to your local hospital

If your GP isn't sure what's wrong with you they will probably refer you to your local hospital for tests and to see a gastroenterologist. Gastroenterologists are specialists in diseases and disorders of the digestive system, including the stomach, intestines, liver and pancreas.

The specialist will probably ask you the same questions you were asked by your GP before giving you a physical examination. They will then decide what tests and investigations you need to work out what is causing your symptoms. It may take several different tests before you are given a definite diagnosis.

Getting admitted to hospital

Sometimes people get admitted to hospital, perhaps even as an emergency, because they are very unwell but at the time the doctors don't know what is wrong.

For example, jaundice may be the first sign that something is wrong and it can come on very quickly. Or someone might go into hospital because they have severe pain or persistent nausea and vomiting that can't be explained.

It is only once they are there that the specialists can assess their symptoms and do whatever tests are needed to enable them to reach a diagnosis.  

Depending on the hospital people are usually admitted to a medical or surgical assessment unit. Or they might come in to Accident and Emergency if they've become ill very suddenly. The medical team will assess them, treat the pain or other symptoms, and do some initial tests, such as an ultrasound scan. They will then be referred to a specialist (upper gastrointestinal or hepatobiliary) team for further investigations.  

Being referred to a specialist centre

Once someone has been diagnosed with pancreatic cancer they should have their case reviewed at a cancer centre with a specialist hepatobiliary team. This may involve an appointment at the regional specialist centre or your local specialist and the specialist team at the regional centre may discuss your scans together without you having to attend the regional centre. Find out more about regional specialist centres and treatment teams here.

Information about the tests and investigations used to diagnose pancreatic cancer can be found here.