Project summary review: Multi-Centre study to test if genetic markers accurately predict mucinous cysts

Provide feedback on a project summary looking to determine if genetic information in the tissue of the cyst wall can improve the identification of mucinous (a type of protein) pancreatic cysts, allowing them to be identified earlier.

The project

Dr Suresh Vasan Venkatachalapathy is applying to the Research for Patient Benefit (RFPB) programme to fund his research. He is looking for feedback on this project which aims to determine if tissue of the cyst wall can improve the identification of mucinous (a type of protein) pancreatic cysts.

There are 2 main types of pancreatic cysts: mucinous (these produce mucin, a type of protein) and non-mucinous. Both are benign but mucinous cysts can later become cancers. However, current methods are poor at distinguishing between mucinous and non-mucinous cysts. Suresh and his team have already performed an initial study where they were able to accurately identify mucinous cysts that led to cancer. They would like to replicate these results to a larger study in the UK, using 10-15 hospitals.

Dr Suresh Vasan Venkatachalapathy and his team at Nottingham University Hospitals NHS trust would like to replicate these results to a larger study in the UK, using approximately 10-15 hospitals to do so.

Next steps

No scientific background or prior experience is needed to take part in this opportunity.

If you would like to give your feedback on this project, please contact the Research Team (research@pancreaticcancer.org.uk) quoting the involvement reference ‘RFPB Vasan’. We will then email you the lay summary and any specific questions Dr Suresh Vasan Venkatachalapathy would like you to consider. Please return your responses to the research team by Thursday 16th November 2023.