Login to Pancreatic Cancer UK

Types of pancreatic cancer pain

There are a few types of pain that people with pancreatic cancer may have. These include nerve pain, soft tissue pain and bone pain. Pain can last some time, or it can come and go quickly in short bursts, with or without warning. Tell your doctor about any pain you have, or if your pain changes.

"Get help as soon as possible for your pain, the earlier it’s treated the better. There’s nothing wrong with asking for help.’’

Background pain

Background pain is ongoing pain that you can manage with regular pain relief. If it isn’t fully controlled, you may have pain shortly before your next dose of pain relief is due. If this happens, you may need a different dose or type of pain relief.

Breakthrough pain

Sometimes, you might get short bursts of severe pain that come on quickly and last for a few minutes or a few hours. This is called breakthrough pain, as it “breaks through” your regular pain relief. You may not know when you’re going to get breakthrough pain.

Treatment for breakthrough pain includes some opioid painkillers, such as morphine or oxycodone

Tell your doctor or nurse as much as you can about your pain. This will help them give you the right treatment. If you are getting a lot of breakthrough pain, you may need a different dose or type of pain relief. It can help to keep a diary of your pain to share with your doctor or nurse.

Incident pain

Incident pain is similar to breakthrough pain but it is caused by an activity, like moving around. If you know what is likely to cause pain, you may be able to prevent it by taking fast acting (immediate release) painkillers 20 to 30 minutes before doing that activity, or by changing the activity.

Nerve (neuropathic) pain

Many people with pancreatic cancer have some nerve pain. This is also called neuropathic pain.

There is a bundle of nerves, called the coeliac plexus, behind the pancreas. These nerves send messages from the pancreas to the brain. Pancreatic cancer can damage the coeliac plexus, causing pain.

Nerve pain can come and go and can be difficult to describe. Some people say it feels like a burning, shooting or stabbing pain, or like pins and needles.,

Nerve pain can be treated with opioid painkillers, and other drugs that help manage pain.

A nerve block is a treatment that blocks nerves from sending messages to the brain, and so treats pain. This may be used if painkillers aren’t controlling nerve pain, or if the side effects of painkillers are hard to deal with.

Soft tissue pain

If pancreatic cancer spreads to nearby organs, like the liver or bowel, it can cause a type of pain called soft tissue (visceral) pain. The pain may feel deep, squeezing, aching or cramping. You may find it difficult to say exactly where the pain is coming from.

Soft tissue pain can sometimes cause pain in another part of the body. For example, you may feel pain in your neck or shoulder. This is called referred pain.

Treatments for soft tissue pain can include painkillers and nerve blocks. Drugs called anti-spasmodic drugs are sometimes used to help with tummy cramps and pain.

“My husband had pain in his shoulder. Now you wouldn’t think about pain in the shoulder, with pancreatic cancer in the stomach area. You think all the pain’s going to be where the problem is.”

Bone pain

For some people, pancreatic cancer can spread to the bone, causing pain. But this is not very common. Some chemotherapy drugs can also cause bone pain. People describe bone pain as aching, throbbing, or cramping. You may have an area that feels tender to touch.

Treatments for bone pain include painkillers  and radiotherapy[link to other ways to manage pain].

Questions to ask

  • What type of pain do I have?
  • How can my pain be treated?

More information on pain and pancreatic cancer

Who can help you to deal with pain?

What causes pancreatic cancer pain?

Types of pancreatic cancer pain

Talking about pain

Painkillers for pancreatic cancer

Nerve blocks 

Other types of pain relief

Things you can do yourself to deal with pain

Updated February 2019

To be reviewed February 2021

Information Standard