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Completed research projects

Find out more about our recently completed projects:

New cells models for the development of personalised treatments for pancreatic neuroendocrine tumours (PanNETs)

Dr Paul Newey

Investigating personalised therapies in mouse models of pancreatic cancer

Mr Douglas Morran, working with Professor Owen Sansom at the Beatson Institute for Cancer Research in Glasgow

Immunotherapy of pancreatic cancer using chimeric antigen receptor engrafted T-cells targeted against the avBeta6 integrin

Dr John Maher

Can multiplex deep sequencing of circulating free DNA detect pancreatic cancer at an early stage?

Professor Jacqueline Shaw

The detection, imaging and therapy of pancreatic cancer

Professor Roy Bicknell

Modelling heterotypic cell-cell interactions in vivo at the initial stages of pancreatic cancer

Dr Catherine Hogan

Can protein profiling enable future screening of newly diagnosed diabetics for pancreatic cancer?

Dr William Greenhalf and Dr Eithne Costello

Myosteatosis and muscle wasting in pancreatic cancer: murderer, mediator or mirror?

Professor Kenneth Fearon and Professor Tom Preston

Molecular imaging biomarkers of gemcitabine resistance in advanced mouse models of pancreatic adenocarcinoma

Dr Bart Cornelissen

Defining a new role for JNK signalling in acinar plasticity

Dr Cathy Tournier

PanORAMA project: Pancreatic Cancer Predisposition, Obesity-Related Deposition Assessment using Magnetic Resonance ImAging

Dr Andrew Renehan

Personalising treatment for pancreatic cancer with cancer stem cells

Professor Christopher Heeschen

Humanising the mouse glycome: the search for new cancer biomarkers

Professor David Tuveson

Evaluating and combining serum biomarkers for early pancreatic cancer detection

Dr Eithne Costello and Dr John Timm

Exploitation of the initiation of DNA replication for the treatment of pancreatic cancer

Dr Steve Pereira

A novel viro-immunotherapy for pancreatic cancer using a new generation of oncolytic vaccinia virus expressing the immunomodulatory gene IL-21

Dr Yaohe Wang

Novel biomarker discovery for the early detection of pancreatic cancer

Dr David Tuveson

Interrogation of UKCTOCS serum bank for existing and novel markers of Pancreatic Ductal Adenocarcinoma (PDAC)

Professor Steve Pereira

New markers of sensitivity to treatment in pancreatic cancer

Dr Chiara Braconi

MicroRNA profiling in pancreatic stellate cells: validation and assessment of potential to predict response to treatment

Professor Eithne Costello

Personalising treatment for pancreatic cancer with cancer stem cells

Professor Christopher Heeschen

Characterisation of Subtype-Specific Metabolism and Associated Therapeutic Targets in Pancreatic Ductal Adenocarcinoma

Dr Anguraj Sadanandam

Investigating pancreatic cancer stem cells from blood

Professor Christopher Heeschen

Developing an immunotherapy treatment for pancreatic cancer

Dr Alexandra Aicher