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Evaluating and combining serum biomarkers for early pancreatic cancer detection

Recipients: Dr Eithne Costello and Dr John Timms

Host Institution: The Department of Gynaecological Oncology, University College London, in partnership with the Division of Surgery and Oncology, Liverpool University.

Title: Evaluating and combining serum biomarkers for early pancreatic cancer detection

Type of award: 2010 Research Grant

Funding: £150,000 awarded over 18 months

This project aims to further develop recent work to identify serum biomarkers of pancreatic cancer with a view to earlier diagnosis. It is based on new methods that allow the measurement of many different proteins from small samples of blood serum and findings from a previous study. This study strongly advocated the use of different markers, such as CA19-9, in a combined panel of biomarkers, to be better predictors of cancer than any particular marker on its own. "This Pancreatic Cancer UK funding is essential to allowing assessment of potential cancer biomarkers that will hopefully lead to the development of blood tests for the early detection of pancreatic cancer".