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A novel viro-immunotherapy for pancreatic cancer using a new generation of oncolytic vaccinia virus expressing the immunomodulatory gene IL-21

Recipient: Dr Yaohe Wang

Host Institution: Queen Mary, University of London

Title: A novel viro-immunotherapy for pancreatic cancer using a new generation of oncolytic vaccinia virus expressing the immunomodulatory gene IL-21

Type of award: 2009 Research Grant

Funding: £246,280 awarded over three years

The project aims to develop a new generation of treatment that will block new blood vessel formation and inhibit growth of tumours. The team are using a novel approach with a modified common cold virus to attack the tumour. The intention, with the help of this funding, is to turn promising research into proof of concept for an effective treatment of pancreatic cancer. "This funding will bolster the translation of some of our most promising research and hopefully improve the prognosis of this dismal cancer".