Research grant type
Research grant locations
Professor Eric O’Neill
Understanding the impact of the immune system on response to treatment
This project will investigate how the immune system can prevent chemotherapy treatments from working properly.
Professor Andrew Biankin
Finding the right treatment for the right patient in pancreatic cancer
This project aims to identify a set of biomarkers that characterise different pancreatic cancers.
Professor Duncan Jodrell
Investigating potential new combination therapies for the treatment of pancreatic cancer
Charles Dunlop will investigate how DNA repair mechanism enables cancer cells to build up a resistance to chemotherapy treatment.
Professor Juan Valle and Dr Mairéad McNamara
Improving outcomes in patients with a diagnosis of pancreatic cancer - The ‘Collins Pancreatic Cancer UK' Scholarship
Professor Juan Valle and Dr Mairéad McNamara will investigate the impact of FOLFIRINOX on patients outcomes.
Nutritional Therapy Research
Lynne McCallum will research the impact of involving a dietician in the early diagnosis and treatment of dietary symptoms and enzyme insufficiency in patients with pancreatic cancer.
Professor Zhengming Chen and Dr Michael Holmes
Development of a blood test for the early detection of pancreatic cancer
What we are trying to achieve: This project will investigate whether a blood test can identify individuals with pancreatic cancer before they start to experience symptoms, which could allow them to undergo potentially curative surgical treatment.
Dr Derek Grose
Using PET scans to determine treatment response to preoperative radiotherapy and chemotherapy
This project investigates a new technique to identify areas of pancreatic cancer tumours with low oxygen supply, and whether this technique can predict a patient’s response to chemotherapy treatment.
Dr Gillian Prue
PRECISE: PancREatic Cancer: Individualised Supervised Exercise: a feasibility study
The team in Belfast will test a bespoke exercise programme for people with pancreatic cancer who have undergone surgery and are receiving chemotherapy. The purpose of this is to improve the resilience of patients, helping them minimize side effects and maximize chemotherapy.
Dr Robin Ketteler
Cutting off the energy supply to pancreatic cancer cells
Pancreatic cancer cells undergo a process called autophagy where they essentially eat parts of themselves to ensure energy supply and survival. The team at UCL aim to find a molecule that stops the autophagy process putting the cancer cells under stress and causing them to die.
Dr Claire Connell
Understanding changes to metabolism and immune function in patients with pancreatic adenocarcinoma
The team will use state of the art clinical research facilities to understand the role the immune system plays in causing the weight loss, which is independent of calorie intake, associated with pancreatic cancer.
Professor Gail ter Haar
Combining viruses and ultrasound to better target and destroy pancreatic tumours
The team at the ICR aim to use ultrasound to break down the barriers surrounding pancreatic tumors, thereby allowing specially engineered viruses to target the cancerous cells and initiate an immune chain reaction that destroys them.
Dr Siim Pauklin
Early detection of pancreatic cancer by analysing DNA taken from patient blood
The team at Oxford have proposed a novel approach that will assess how DNA modifications produce so called ‘cancer stem cells’ that have the ability to change how they grow and duplicate, which is one of the first steps in cancer development. They will then look at whether these modifications could potentially be detected in the blood at an early stage.
Mr Siong-Seng Liau
Strengthening the immune system’s ability to fight pancreatic cancer
The team want to understand more about preventing pancreatic cancer cells from switching off the expression of certain genes, which allow them to evade the immune system and render immunotherapy ineffective.
Future Leaders Academy 2017
In September 2017 we announced the launch of the Pancreatic Cancer UK Future Leaders Academy, a new training programme for Future Leaders at the world-leading Beatson Institute in Glasgow.