What treatments are there for pancreatic cancer?

There are different treatment options for people with pancreatic cancer. We explain the different treatments available, including surgery, chemotherapy and radiotherapy.

To work out the best pancreatic cancer treatment for you, your doctors will look at your scans to work out the type of pancreatic cancer you have and the stage of the cancer. They will also look at other things such as your age, and your general health and fitness.

An elderly man in a black jacket sits in a medical office, conversing with a healthcare professional. A computer monitor is visible in the background.

What happens if surgery isn’t an option?

If you can't have surgery to remove pancreatic cancer, you may be able to have chemotherapy to try to control the cancer. There are also treatments to manage any symptoms.

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What care should I get for pancreatic cancer?

It can be hard understanding the healthcare system. Find out about the medical team and how to access different care and support.

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Could I take part in a clinical trial?

Clinical trials for pancreatic cancer show us what treatments and care do and don’t work. Find out about trials and use our Trial Finder to search for current trials.

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What is the best treatment for pancreatic cancer? 

The best treatment for your cancer will depend on your diagnosis. Surgery to remove pancreatic cancer is the best treatment for people with pancreatic cancer that has not spread outside the pancreas. You may also have chemotherapy before and/or after surgery, and some people may be offered radiotherapy. 

If surgery is not possible, you may be able to have treatments for the cancer, such as chemotherapy or radiotherapy. This will depend on the stage of your cancer and how well you are. The aim of treatment will be to control the growth of your cancer and help you live longer. You will also have treatment to manage any symptoms you have. 

Questions to ask your doctor or nurse


  • What treatment do you recommend for me? 
  • What is the likely result of this treatment? 
  • What are the benefits and risks of this treatment? 
  • What are the possible side effects? 
  • Can I get a second opinion? How do I go about getting one? 
  • Are there any clinical trials that I could take part in? 
  • What happens next? 
  • Who should I contact if I have any questions? 

References


We have listed some of the references to the sources used to write this information. If you would like the full list of references, email us at publications@pancreaticcancer.org.uk 

  • Biagi JJ et al. Adjuvant chemotherapy and radiotherapy in resected pancreatic ductal adenocarcinoma: A systematic review and clinical practice guideline. Curr. Oncol. 2023;30(7):6575-6586. doi:10.3390/curroncol30070482 
  • Zhang B, Zhou F, Hong J, et al. The role of FOLFIRINOX in metastatic pancreatic cancer: a meta-analysis. World J Surg Oncol 2021;19(1):182. doi: 10.1186/s12957-021-02291-6 
  • Chen Z, Lv Y, Li H, Diao R, Zhou J, Yu T. Meta-analysis of FOLFIRINOX-based neoadjuvant therapy for locally advanced pancreatic cancer. Medicine 2021;100(3):E24068. doi:10.1097/MD.0000000000024068 

Published March 2026 

To be reviewed March 2029