Painkillers for pancreatic cancer pain

Find out about the types of painkillers used for pancreatic cancer, and how they are used.

Key facts

  • There are different types of painkillers used to treat pancreatic cancer pain.
  • You are likely to take more than one type of painkiller to help your pain.
  • Non-opioid painkillers include paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen or naproxen.
  • Opioid painkillers include morphine and oxycodone.
  • There are also other medicines that are usually used to treat other health conditions, but can also be used to relieve pain.

How do I take painkillers?

Your doctor or nurse will tell you how and when to take your painkillers, and how long the pain relief should last. They should also explain any possible side effects.

It’s important to follow your doctor’s instructions. For example, you may need to take your painkillers at regular times, to stop the pain coming back when the medicine wears off. Pain can be harder to control if you wait until your pain is bad before taking painkillers.

Your doctor and nurse should check your pain regularly, to make sure your painkillers are working. Tell them if your pain gets worse. They will look at your painkillers and may increase the dose or add different painkillers.

Quotemarks Created with Sketch.
Quotemarks Created with Sketch.

“Take painkillers as soon as you experience any pain. Don’t feel you have to suffer in silence or that it’s better not to take them. Dealing with pain quickly and effectively will improve the quality of your life.”

What is a syringe pump?

A syringe pump (also called a syringe driver) provides a steady flow of painkillers. It is a small battery operated machine which is attached to a needle that is put under the skin. This needle is then replaced with a plastic tube. A doctor or nurse will set it up for you.

A syringe pump is used if you can’t swallow medicines, are being sick or your bowel can’t absorb the medicines. It’s also used if your drugs can only be given by injection.

A syringe pump can also be used for other medicines, such as anti-sickness medicine. You can move around with a syringe pump, and can use it at home.

Diagram of a syringe pump

Diagram showing syringe pump and how it attaches to the body

What can I do?

  • Tell your medical team as soon as you can about any new pain or any pain that has got worse. This will help them manage it as well as possible.
  • Keep a record of things like where the pain is, how bad it is on a scale of 0 to 10, how it affects everyday things like sleeping, and whether anything makes it better or worse.
  • You could use a pain diary or mobile phone app to record your pain. Ask your doctor or nurse if they can recommend anything.
  • If you are taking lots of medicines, you could use a pill box, to help you remember when to take them. Ask your nurse for any other tips.

Side effects of painkillers

Painkillers can cause side effects. Ask your doctor or nurse about side effects of the painkillers you are taking. Tell them if you get any side effects. They may prescribe medicine to prevent or treat side effects, or they may change the painkiller. Don’t stop taking your painkillers without speaking to your doctor or nurse first.

Tell your doctor or pharmacist about any other medicines you are taking. Medicines can affect each other, causing more side effects or stopping another drug from working. This includes drugs you can buy at your local pharmacy, like ibuprofen and paracetamol, and some herbal remedies.

Updated April 2025

To be reviewed April 2028